Publications
Bibliography of Selected Relevant Publications
5.1 Oncology
5.2 Immunology
5.3 Neurodegeneration
5.3.14 Wong PK: Antioxidant
compound slows cell death: International
Innovation February
2010, ISSN 2041-4551: 60-62
5.3.13 Reddy PV, Lungu G, Kuang X, Stoica G, Wong PK: Neuroprotective effects of the drug GVT (monosodium luminol) is mediated by the stabilization of Nrf2 in astrocytes: Neurochemistry International 2010, Mar 6 [Epub ahead of print]
5.3.12 Lungu G, Kuang X, Stoica G, Wong PK: Monosodium luminol upregulates the expression of Bcl-2 and VEGF in retrovirus-infected mice through downregulation of corresponding miRNAs: Acta Virologica 2010, 54(1):27-32
5.3.11 Kuang X, Scofield VL, Yan M, Stoica G, Liu N, Wong PK: Attenuation of oxidative stress, inflammation and apoptosis by minocycline prevents retrovirus-induced neurodegeneration in mice: Brain Res 2009, 1286:174-184
5.3.10 Kim J, Wong PK: Oxidative stress is linked to ERK1/2-p16 signaling-mediated growth defect in ATM-deficient astrocytes. J. Biological Chemistry 2009, 284(21):14396-14404
5.3.9 Scofield VL, Yan M, et al: The drug monosodium luminol (GVT®) preserves thymic epithelial cell cytoarchitecture and allows thymocyte survival in mice infected with the T cell-tropic, cytopathic retrovirus ts1: Immunology Letters 2009, 122(2):159-169
5.3.8 Yan M, Shen J, Person MD, Kuang X, Lynn WS, Atlas D, Wong PK: Endoplasmic reticulum stress and unfolded protein response in Atm-deficient thymocytes and thymic lymphoma cells are attributable to oxidative stress: Neoplasia 2008, 10(2):160-167
5.3.7 Oates PJ: Aldose reductase, still a compelling target for diabetic neuropathy: Current Drug Targets 2008, 9:14-36
5.3.6 Sredni B, Geffen-Aricha R, Duan W et al: Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson’s disease models: FASEB J. 2007, 21:1870-1883
5.3.5 Antony J et al: The human endogenous retrovirus envelope glycoprotein, syncytin-1, regulates neuroinflammation and its receptor expression in multiple sclerosis: a role for endoplasmic reticulum chaperones in Astrocytes: J. Immunology 2007, 10:1210-1224
5.3.4 Eljaschewitsch E et al: The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells: Neuron 2006, 49:67-69
5.3.3 Qiang W, Kuang X, Liu J et al: Astrocytes survive chronic infection and cytopathic effects of the ts1 mutant of the retrovirus Moloney murine leukemia virus by upregulation of antioxidant defenses: J. Virology 2006, 80(7):3273–3284
5.3.2 Jiang Y, Scofield VL, Yan M, et al: Retrovirus-induced oxidative stress with neuroimmunodegeneration is suppressed by antioxidant treatment with a refined monosodium α -luminol (Galavit): J. Virology 2006, 80(9):4557–4569
5.3.1 Ramirez B et al: Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation: J. Neuroscience 2005, 258:1903-1911
5.4 Wound Care
/ CABG
5.4.4 Scofield VL, Yan M, Kuang X, Kim SJ, Wong PK: The drug monosodium luminol (GVT) preserves crypt-villus epithelial organization and allows survival of intestinal T cells in mice infected with the ts1 retrovirus: Immunology Letters 2009, 122(2):150-158.
5.4.3 Ramlawi, B., Otu, H., Mieno, S. et al.: Oxidative
stress and atrial fibrillation after cardiac surgery:
a case-control study. Ann. of Thorac.Surg. (2007)
84:1166-73.
5.4.2 Parolari, A., Camera, M., Alamanni, F. et al.:
Systemic inflammation after on-pump and off pump coronary
bypass surgery: a one month follow-up. Ann. of Thorac.
Surg. (2007)
84:823-828.
5.4.1 Kapoor, M.C. and Ramachandran, T.R.: Inflammatory
response to cardiac surgery and strategies to overcome
it: Ann. of Cardiac Anesthesia. (2004) 7:113-128.
5.5 Metabolic
Syndrome
5.5.6 Ajmo JM, Liang X, et al: Resveratrol alleviates alcoholic fatty liver in mice: Am J Physiol Gastrointest Liver Physiol 2008, 295:G833-G842
5.5.5 Lo JC, Wang Y, Tumanov AV et al: Lymphotoxin b receptor–dependent control of lipid homeostasis: SCIENCE 2007, 316(13):285-288
5.5.4 Pelosi L, Giacinti C, Nardis C et al: Local expression of IGF-1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines: FASEB J. 2007, 21:1393-1402
5.5.3 Suckling K: Drug discovery in the metabolic syndrome: context and some recent developments: Expert Opin. Ther. Targets. 2007, 11(6):801-808
5.5.2 Schneider JG, Finck BN, Ren J et al: ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome: Cell Metab. 2006, 4:377-389
5.5.1 Kim M-S, Park J-Y, Namkoong C, et al: Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase: Nature Medicine 2004, 10(7)727-733
5.6 Metabolic Syndrome
5.7 COPD/Bronchitis
5.7.2 Fabbri L, Hogg JC, Jenkins C et al: Global initiative for chronic obstructive lung disease: 2007, 18, 25
5.7.1 Hiemstra PS: Meeting Report: World Congress on Lung Health and 10th ERS Annual Congress: Respir. Res. 2000, 1:178–179
5.8 Ocular Disease
5.8.1 Garcia da Silva E, Gionfriddo JR, Hudachek SF, Gustafson DL, Olea-Popelka F, Powell CC, Scofield VL: Ocular penetration of topical GVT®: Manuscript in Preparation, September 2009
5.8.2 Gionfriddo JR, Freeman KS, Groth A, Scofield VL, Alyahya K, Madl JE: alpha-Luminol prevents decreases in glutamate, glutathione, and glutamine synthetase in the retinas of glaucomatous DBA/2J mice: Vet Ophthalmol. 2009, 12(5):325-332
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